Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (10) GO Terms (22) Nucleotides (180) Proteins (45) Interactants (497) Wiki
Gene Symbol:

Gene Name:
NDC80 kinetochore complex component NUF2

xnuf2 , cdca1 , ct106 , nuf2r , nuf2-a , nuf2-b ( Add synonyms , Nomenclature history )

Gene Function:
Centromere-associated protein NUF2

Protein Function :
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organ...[+]

Loading ...


External Links:
Xenbase Gene ID XB-GENE-1001441 XB-GENE-1001444 XB-GENE-6252105
Gene Symbol nuf2 nuf2.L nuf2.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100145128
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. Swiss-Prot Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nuf2 nuf2.L nuf2.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards NUF2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Nuf2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Nuf2 Ensembl
ZFIN, AGR nuf2 ZFIN Ensembl
fruit fly
FLYBASE Nuf2 Ensembl
First The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity., Genes Dev 2003  
Most Recent From meiosis to mitosis - the sperm centrosome defines the kinetics of spindle assembly after fertilization in Xenopus., J Cell Sci 2016            
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 7 terms 5 terms
KEGG Pathways K11548 K11548 K11548
KOG [D] Centromere-associated protein NUF2
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nuf2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info