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Summary Expression Gene Literature (47) GO Terms (39) Nucleotides (156) Proteins (53) Interactants (748) Wiki
Gene Symbol:

Gene Name:
tumor protein p63

trp63 , ket , tp73l , Xp63 , p63 , np63 ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator tha...[+]

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Disease Ontology:
ADULT syndrome [+]


External Links:
Xenbase Gene ID XB-GENE-479868 XB-GENE-865317 XB-GENE-17341311
Gene Symbol tp63 tp63.L tp63.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100497737
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tp63 tp63.L tp63.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards TP63 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Trp63 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Tp63 Ensembl
ZFIN, AGR tp63 ZFIN Ensembl
GEISHA TP63 Ensembl
fruit fly
First Pathway of B1-Alu expression in microinjected oocytes: Xenopus laevis proteins associated with nuclear precursor and processed cytoplasmic RNAs., Mol Cell Biol 1988  
Most Recent Signaling Control of Mucociliary Epithelia: Stem Cells, Cell Fates, and the Plasticity of Cell Identity in Development and Disease., Cells Tissues Organs 2021  
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 38 terms 12 terms 11 terms
KEGG Pathways K14801 [+] K10149 K10149
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tp63
Antibodies Tp63 Ab1 , Tp63 Ab3 Tp63 Ab1 , Tp63 Ab3 Tp63 Ab3
Morpholinos tp63 MO1 , tp63 MO2 , tp63 MO3 tp63 MO1 , tp63 MO2 , tp63 MO3 tp63 MO3
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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