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Summary Expression Gene Literature (203) GO Terms (76) Nucleotides (135) Proteins (47) Interactants (1767) Wiki
Gene Symbol:

Gene Name:
LIM homeobox 1

Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1 ( Add synonyms , Nomenclature history )

Gene Function:
LIM and homeodomain containing transcription factor

Protein Function :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]

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External Links:
Xenbase Gene ID XB-GENE-482482 XB-GENE-856460 XB-GENE-17343236
Gene Symbol lhx1 lhx1.L lhx1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101708
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lhx1 lhx1.L lhx1.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas028k15      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards LHX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Lhx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Lhx1 Ensembl
ZFIN, AGR ZFIN, AGR lhx1a lhx1b ZFIN Ensembl
fruit fly
First The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos., Genes Dev 1992                
Most Recent Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021                          
All View All Papers 43 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 11 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 68 terms 6 terms
KEGG Pathways K09372 K09372
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lhx1
Antibodies Lhx1 Ab1 , Lhx1 Ab3 Lhx1 Ab1 , Lhx1 Ab3 Lhx1 Ab3
Morpholinos lhx1 MO2 , lhx1 MO1 lhx1 MO2 , lhx1 MO1 lhx1 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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