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Summary Expression Gene Literature (113) GO Terms (24) Nucleotides (377) Proteins (52) Interactants (911) Wiki
Gene Symbol:

Gene Name:
frizzled class receptor 7

Fz-7 , Xfz7 , frizzled-7 , frizzled7 , frizzled 7 , frz7 , frz-7 , fz7 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Acts in both canonical and non-canonical Wnt pathways. Although different papers report differing Wnt preferences, wnt5a, wnt8b and wnt11 have been proposed as synergists. In...[+]

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External Links:
Xenbase Gene ID XB-GENE-483731 XB-GENE-483735 XB-GENE-17333315
Gene Symbol fzd7 fzd7.L fzd7.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549495
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine fzd7 fzd7.L fzd7.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tneu065e03      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards FZD7 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Fzd7 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Fzd7 Ensembl
ZFIN, AGR ZFIN, AGR fzd7a fzd7b ZFIN Ensembl
fruit fly
First Two novel Xenopus frizzled genes expressed in developing heart and brain., Mech Dev 1999      
Most Recent The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled., Development 2020                                    
All View All Papers 32 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 16 terms 6 terms
KEGG Pathways K02432 [+] K02432 K02432
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks fzd7
Antibodies fzd7 Ab1 fzd7 Ab1 fzd7 Ab1
Morpholinos fzd7 MO6 , fzd7 MO7 fzd7 MO1 , fzd7 MO3 , fzd7 MO4 fzd7 MO2 , fzd7 MO5
ORFs fzd7 ORF1 fzd7 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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