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Summary Expression Gene Literature (123) GO Terms (23) Nucleotides (661) Proteins (62) Interactants (709) Wiki
XB-GENEPAGE-485872
Gene Symbol:
pkm

Gene Name:
pyruvate kinase M1/2

Synonyms:
cthbp , pyruvate kinase , pk3 , pk , pk ( Add synonyms , Nomenclature history )

Gene Function:
Pyruvate kinase

Protein Function :
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP.



Interactants:
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Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-485873 XB-GENE-17331006 XB-GENE-485877
Gene Symbol pkm pkm.L pkm.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549224
380274
399448
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq RefSeq RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pkm pkm.L pkm.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PKM OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pkm MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pkm Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pkma pkmb ZFIN Ensembl
chicken
GEISHA PKLR Ensembl
fruit fly
Publications
First In vivo phosphorylation of a synthetic peptide substrate of cyclic AMP-dependent protein kinase., Proc Natl Acad Sci U S A 1978  
Most Recent Phosphoproteomic Analysis of Xenopus laevis Reveals Expression and Phosphorylation of Hypoxia-Inducible PFKFB3 during Dehydration., iScience 2020                  
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 5 terms 5 terms
PANTHER pkm
KEGG Pathways K00873 K00873 K00873
KOG [G] Pyruvate kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pkm
Antibodies Pkm Ab1 Pkm Ab1
ORFs pkm.L ORF1 pkm.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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