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Summary Expression Gene Literature (11) GO Terms (28) Nucleotides (83) Proteins (35) Interactants (179) Wiki
XB-GENEPAGE-486051
Gene Symbol:
lrp2

Gene Name:
LDL receptor related protein 2

Synonyms:
megalin , dbs , gp330 ( Add synonyms , Nomenclature history )

Gene Function:
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Donnai-Barrow syndrome

OMIM:
DONNAI-BARROW SYNDROME

External Links:
 
Xenbase Gene ID XB-GENE-486052 XB-GENE-6253809 XB-GENE-17344795
Gene Symbol lrp2 lrp2.L lrp2.S
Chromosome Chr9 chr9_10L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100489914
100126618
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lrp2 lrp2.L lrp2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards LRP2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lrp2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lrp2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR lrp2a lrp2b ZFIN Ensembl
chicken
GEISHA LRP2 Ensembl
fruit fly
Publications
First NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor., J Biol Chem 1990  
Most Recent Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Development 2021  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 0 term 0 term
PANTHER lrp2
KEGG Pathways K06233
KOG [T] Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lrp2
Morpholinos lrp2 MO1 lrp2 MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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