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Summary Expression Phenotypes Gene Literature (34) GO Terms (14) Nucleotides (101) Proteins (46) Interactants (557) Wiki
XB-GENEPAGE-486780
Gene Symbol :
axin1

Gene Name :
axin 1

Synonyms:
xAxin , axin , fused ( Add synonyms , Nomenclature history )

Gene Function:
negative regulator of the wnt signaling pathway

Protein Function :
Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via tw...[+]


InterPro :
VDCC L a1su , VDCC L a1F , VDCC a1su IQ , GPHH dom [+]

Interactants:
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Diseases: 


Disease Ontology:
hepatocellular carcinoma

OMIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info