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Summary Expression Gene Literature (3) GO Terms (21) Nucleotides (79) Proteins (36) Interactants (11) Wiki
XB-GENEPAGE-5787149
Gene Symbol:
bace1

Gene Name:
beta-site APP-cleaving enzyme 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
aspartyl protease

Protein Function :



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5787150 XB-GENE-17330537 XB-GENE-17330538
Gene Symbol bace1 bace1.L bace1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 779940
108696469
108697592
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine bace1 bace1.L bace1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards BACE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bace1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bace1 Ensembl
zebrafish
ZFIN, AGR bace1 ZFIN Ensembl
chicken
GEISHA BACE1 Ensembl
fruit fly
Publications
First Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells., J Mol Neurosci 2006  
Most Recent Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer''s disease treatment., Biochim Biophys Acta Mol Basis Dis 2017  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 13 terms 13 terms
PANTHER bace1
KEGG Pathways K04521 K04521 K04521
KOG [O] Aspartyl protease
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks bace1
Mutants Xtr.bace1emHorb
ORFs bace1 ORF1
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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