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Summary Expression Gene Literature (2) GO Terms (10) Nucleotides (122) Proteins (32) Interactants (124) Wiki
XB-GENEPAGE-5887532
Gene Symbol:
dnaaf2

Gene Name:
dynein, axonemal, assembly factor 2

Synonyms:
ktu , cild10 , kintoun ( Add synonyms , Nomenclature history )

Gene Function:
transcription factor

Protein Function :
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before int...[+]



Interactants:
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Diseases: 


Disease Ontology:
Kartagener syndrome [+]

OMIM:
CILIARY DYSKINESIA, PRIMARY, 10; CILD10

External Links:
 
Xenbase Gene ID XB-GENE-5887533 XB-GENE-5887592 XB-GENE-17337670
Gene Symbol dnaaf2 dnaaf2.L dnaaf2.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 779929
100158322
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dnaaf2 dnaaf2.L dnaaf2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DNAAF2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dnaaf2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dnaaf2 Ensembl
zebrafish
ZFIN, AGR dnaaf2 ZFIN Ensembl
chicken
GEISHA DNAAF2 Ensembl
fruit fly
Publications
First A liquid-like organelle at the root of motile ciliopathy., Elife 2018                                
Most Recent Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins., Elife 2020                    
All View All Papers 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 3 terms 0 term
PANTHER dnaaf2
KEGG Pathways K19751 K19751
KOG [S] Uncharacterized conserved protein (alt_id KOG:4356)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dnaaf2
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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