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Summary Expression Phenotypes Gene Literature (0) GO Terms (0) Nucleotides (110) Proteins (27) Interactants (1) Wiki
XB-GENEPAGE-6035125
Gene Symbol :
szt2
Symbol Status : Curated


Gene Name :
SZT2, KICSTOR complex subunit
Name Status : Curated


Synonyms:
SZT2A , SZT2B , EIEE18 , C1orf84 , KIAA0467 [-] ( Add synonyms , Nomenclature history )

Gene Function:
Nucleolar GTPase/ATPase p130. he protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
early infantile epileptic encephalopathy [+]

OMIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 18; DEE18

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:

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