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Summary Expression Gene Literature (9) GO Terms (17) Nucleotides (122) Proteins (33) Interactants (77) Wiki
XB-GENEPAGE-940794
Gene Symbol:
sgo1

Gene Name:
shugoshin 1

Synonyms:
sgol1 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromos...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
chronic atrial and intestinal dysrhythmia

OMIM:
CHRONIC ATRIAL AND INTESTINAL DYSRHYTHMIA; CAID

External Links:
 
Xenbase Gene ID XB-GENE-940795 XB-GENE-940797 XB-GENE-17338099
Gene Symbol sgo1 sgo1.L sgo1.S
Chromosome Chr6 chr6L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100135357
735145
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sgo1 sgo1.L sgo1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SGO1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sgo1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sgo1 Ensembl
zebrafish
ZFIN, AGR sgo1 ZFIN Ensembl
chicken
GEISHA SGO1 Ensembl
fruit fly
Publications
First Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis., Cell 2004  
Most Recent The Borealin dimerization domain interacts with Sgo1 to drive Aurora B-mediated spindle assembly., Mol Biol Cell 2020            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 7 terms 0 term
PANTHER sgo1
KEGG Pathways K11580 K11580
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sgo1
ORFs sgo1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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