Gene Symbol : letm1 Gene Name : leucine zipper-EF-hand containing transmembrane protein 1 Synonyms: ( Add synonyms , Nomenclature history ) Gene Function: Ca2+-binding transmembrane protein LETM1/MRS7 Protein Function : Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion. Required for the maintenance of the tubular shape and cristae organization. Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion. Required for the maintenance of the tubular shape and cristae organization. [-] InterPro : EF hand dom , EF Hand 1 Ca BS , LETM1 , EF-hand-dom pair [+] , LETM1 RBD [-] Interactants: Loading ... Diseases:  Disease Ontology: Wolf-Hirschhorn syndrome OMIM: WOLF-HIRSCHHORN SYNDROME; WHS External Links: ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD

Expression	Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information	Xenbase Expression Details In situ images Single cell data at SPRING

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