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Summary Expression Gene Literature (2) GO Terms (18) Nucleotides (166) Proteins (34) Interactants (629) Wiki
XB-GENEPAGE-955660
Gene Symbol:
uba5

Gene Name:
ubiquitin like modifier activating enzyme 5

Synonyms:
ube1dc1 ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-activating enzyme

Protein Function :
E1-like enzyme which specifically catalyzes the first step in ufmylation. Activates ufm1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side ch...[+]



Interactants:
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Diseases: 


Disease Ontology:
autosomal recessive spinocerebellar ataxia 24 [+]

OMIM:
DEVELOPMENTAL AND EPILEPTIC ENCEPHALOPATHY 44; DEE44 [+]

External Links:
 
Xenbase Gene ID XB-GENE-955661 XB-GENE-17343540 XB-GENE-955667
Gene Symbol uba5 uba5.L uba5.S
Chromosome Chr6 chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 448010
734791
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine uba5 uba5.L uba5.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tneu098a04      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards UBA5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Uba5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Uba5 Ensembl
zebrafish
ZFIN, AGR uba5 ZFIN Ensembl
chicken
GEISHA UBA5 Ensembl
fruit fly
FLYBASE Uba5 Ensembl
Publications
First Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., PLoS Genet 2006                                      
Most Recent Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Int J Dev Biol 2014                  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 16 terms
PANTHER uba5
KEGG Pathways K12164 K12164
KOG [H] Molybdopterin biosynthesis-related protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks uba5
Morpholinos uba5 MO1
ORFs uba5 ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info