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Summary Expression Gene Literature (23) GO Terms (23) Nucleotides (378) Proteins (44) Interactants (121) Wiki
XB-GENEPAGE-957400
Gene Symbol:
pum1

Gene Name:
pumilio RNA binding family member 1

Synonyms:
pumh , pumilio , pumilio 1 , pumilio-1 , pumh1 , puml1 , pumilio1 ( Add synonyms , Nomenclature history )

Gene Function:
Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)

Protein Function :
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGU...[+]



Interactants:
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Diseases: 


Disease Ontology:
cerebellar ataxia type 47

OMIM:
SPINOCEREBELLAR ATAXIA 47; SCA47

External Links:
 
Xenbase Gene ID XB-GENE-957401 XB-GENE-17346314 XB-GENE-957405
Gene Symbol pum1 pum1.L pum1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100137097
108708085
394392
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pum1 pum1.L pum1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PUM1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pum1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pum1 Ensembl
zebrafish
ZFIN, AGR pum1 ZFIN Ensembl
chicken
GEISHA PUM1 Ensembl
fruit fly
Publications
First Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein., J Biol Chem 2001  
Most Recent Functions, mechanisms and regulation of Pumilio/Puf family RNA binding proteins: a comprehensive review., Mol Biol Rep 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 1 terms 3 terms
PANTHER pum1
KEGG Pathways K17943
KOG [J] Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pum1
Antibodies Pum1 Ab1 , Pum1 Ab2 , Pum1 Ab3 Pum1 Ab1 , Pum1 Ab2 , Pum1 Ab3
ORFs pum1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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