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Summary Expression Phenotypes Gene Literature (0) GO Terms (6) Nucleotides (329) Proteins (47) Interactants (22) Wiki
XB-GENEPAGE-973906
Gene Symbol :
crbn

Gene Name :
cereblon

Synonyms:
cereblon , mrt2a ( Add synonyms , Nomenclature history )

Gene Function:
Predicted ATP-dependent protease PIL, contains LON domain

Protein Function :
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2 (Probable)...[+]


InterPro :
EF-hand-dom pair , EF-hand dom typ1 , Znf ZZ , PUA-like sf [+]

Interactants:
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Diseases: 


Disease Ontology:
autosomal recessive non-syndromic intellectual disability

OMIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 2; MRT2

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:

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