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Summary Expression Gene Literature (11) GO Terms (13) Nucleotides (174) Proteins (43) Interactants (296) Wiki
XB-GENEPAGE-977104
Gene Symbol:
pum2

Gene Name:
pumilio RNA binding family member 2

Synonyms:
pumilo 2 , pumh2 , puml2 , pumilio-2 , pumilio2 ( Add synonyms , Nomenclature history )

Gene Function:
Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)

Protein Function :
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGU...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-977105 XB-GENE-6486498 XB-GENE-17346076
Gene Symbol pum2 pum2.L pum2.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100496617
100653503
108718259
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pum2 pum2.L pum2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PUM2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pum2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pum2 Ensembl
zebrafish
ZFIN, AGR pum2 ZFIN Ensembl
chicken
GEISHA PUM2 Ensembl
fruit fly
Publications
First Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind., Genomics 2005  
Most Recent Functions, mechanisms and regulation of Pumilio/Puf family RNA binding proteins: a comprehensive review., Mol Biol Rep 2020  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 3 terms 1 terms
PANTHER pum2
KEGG Pathways K17943 K17943
KOG [J] Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pum2
Antibodies Pum2 Ab1 Pum2 Ab1 Pum2 Ab1
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

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