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Summary Expression Gene Literature (1) GO Terms (14) Nucleotides (131) Proteins (27) Interactants (143) Wiki
XB-GENEPAGE-982636
Gene Symbol:
sort1

Gene Name:
sortilin 1

Synonyms:
sortilin , gp95 , ldlcq6 ( Add synonyms , Nomenclature history )

Gene Function:
Sortilin and related receptors

Protein Function :
Receptor for ATP that acts as a ligand-gated ion channel.



Interactants:
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Diseases: 


OMIM:
LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 6; LDLCQ6

External Links:
 
Xenbase Gene ID XB-GENE-982637 XB-GENE-17344029 XB-GENE-4755068
Gene Symbol sort1 sort1.L sort1.S
Chromosome Chr2 chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100490074
100158281
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sort1 sort1.L sort1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards SORT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sort1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sort1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR sort1a sort1b ZFIN Ensembl
chicken
GEISHA SORT1 Ensembl
fruit fly
Publications
First Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation., J Biol Chem 2011  
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 0 term 3 terms
PANTHER sort1
KEGG Pathways K12388 K12388
KOG [R] Sortilin and related receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sort1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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