|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
slc4a4
|
|
laevis
|
NF stage 35 and 36
|
otic vesicle
,
pronephric duct
,
early proximal tubule
,
glomus
,
pronephric kidney
,
[+]
|
slc12a1
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
pronephric duct
,
early distal tubule
,
late distal tubule
,
pronephric kidney
|
irx3
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
hindbrain
,
spinal cord
,
pharyngeal arch
,
late proximal tubule
,
early distal tubule
,
[+]
|
irx2
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
early distal tubule
,
pronephric kidney
|
pax2
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
hindbrain
,
spinal cord
,
pronephric duct
,
pharyngeal arch
,
post-anal gut
,
[+]
|
irx1
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
brain
,
hindbrain
,
midbrain-hindbrain boundary
,
spinal cord
,
pronephric duct
,
[+]
|
mecom
|
|
laevis
|
NF stage 33 and 34
to
NF stage 35 and 36
|
forebrain
,
midbrain
,
hindbrain
,
spinal cord
,
pronephric duct
,
[+]
|
mecom
|
|
laevis
|
NF stage 24
|
forebrain
,
midbrain-hindbrain boundary
,
pronephric mesenchyme
,
cranial neural crest
|
|
|
Fig. 8.
Dominant-negative HNF1B affects expression of proximal and intermediate but not distal tubule markers. (A-R) Whole-mount ISH of Xenopus tadpoles injected with HNF1B-DN mRNA and analysed at stage 34-35 (A-N) or stage 24-25 (O-R) for slc4a4 (A,H), pax2 (B,I) slc12a1 (C,J), irx1 (D,K), irx2 (E,L), irx3 (F,M), evi1 (G,N,Q,R), dll1 (O,P); lateral views of uninjected (A-G,O,Q) and injected (H-N,P,R) sides. Insets show a higher magnification of the anterior pronephric territory. Arrowhead in P indicates the territory where dll1 should be expressed. |