Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
dll1xenopus   

Too many results?Too few results?

Experiment details for dll1

Nrarp is a novel intracellular component of the Notch signaling pathway.

Nrarp is a novel intracellular component of the Notch signaling pathway.

Gene Clone Species Stages Anatomy
dll1.L laevis NF stage 16 Rohon-Beard neuron , neuron , pre-chordal neural plate border , chordal neural plate border , neural plate border , [+]

Display additional annotations [+]
  Figure 2. Expression of Nrarp mirrors that of other Notch pathway genes. Xenopus embryos were stained for the expression of Nrarp RNA using whole-mount in situ hybridization. (A) Nrarp expression at early neurulae stages. Shown is a dorsal view with anterior oriented to the left. Note that Nrarp RNA is expressed at high levels in the neural plate, localizing to the three bilateral domains where the Notch pathway is known to operate during the formation of the primary neurons (M, medial; I, intermediate; L, lateral). In addition, NrarpRNA can be detected in the paraxial mesoderm (PM). (B,C) For comparison, note that the expression pattern of Nrarp is similar to that of XDelta1(B) and ESR1 (C). (D) Expression ofNrarp RNA in a tadpole embryo stained in whole mount. Shown is a side view of the anterior end with anterior oriented to the left. Note expression in the eye (EY), neural tube (NT), and branchial arches (BA). (E) Tissue section of an embryo as in panel Dshows that the expression of Nrarp RNA in the neural tube is confined to the ventricular zone where neurogenesis occurs. (F) Expression of Nrarp occurs at high levels in the outgrowing tailbud where Notch signaling is known to play a role in segmentation. High levels of Nrarp expression are apparent in the most posterior portion of the presomitic mesoderm called the tailbud domain (TBD) and in segments in a region containing prospective somites. This expression pattern in the presomitic mesoderm closely parallels that of XDelta2 and two Notch target genes,ESR4 and ESR5.