|
Gene |
Clone |
Species |
Stages |
Anatomy |
gadd45a
|
|
tropicalis
|
NF stage 9
to
NF stage 10
|
ectoderm
,
cement gland primordium
,
mesoderm
,
non-involuting marginal zone
|
gadd45a
|
|
tropicalis
|
NF stage 17
to
NF stage 18
|
cement gland primordium
,
neural plate
,
preplacodal ectoderm
|
gadd45a
|
|
tropicalis
|
NF stage 20
to
NF stage 21
|
midbrain
,
cement gland
,
circumblastoporal collar
,
pineal gland
,
cloaca
|
gadd45a
|
|
tropicalis
|
NF stage 28
|
otic vesicle
,
retina
,
head region
,
trunk region
,
eye
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
gadd45g
|
|
tropicalis
|
NF stage 12
|
animal cap
|
gadd45g
|
|
tropicalis
|
NF stage 17
to
NF stage 18
|
olfactory placode
,
pineal gland
,
dorsolateral placode region
,
trigeminal placode
,
neural plate
,
[+]
|
gadd45g
|
|
tropicalis
|
NF stage 28
|
olfactory placode
,
otic vesicle
,
retina
,
brain
,
forebrain
,
[+]
|
|
|
Fig. 11. Expression of Gadd45-related genes. A: Weak expression of Gadd45g in the animal cap ectoderm of the blastula (side view).
B: Gadd45a is diffusely expressed in the ectoderm and noninvoluted mesoderm of the gastrula (side view). C,D: Gadd45a is expressed throughout the neural plate, PPE and cement gland (C, anterior view; D, dorsal view). E,F: At neural tube closure, Gadd45a expression in the anterior part of the embryo (E) is enhanced in the cement gland and pineal, and in the posterior part (F) in a patch of paraxial mesoderm (pm) and in mesoderm surrounding the cloaca (arrowhead). G: At neural tube stages, Gadd45g is expressed in the neural tube, including pineal, and multiple placodes (olf, L, Vp, dlp; anterior view). H: At neural plate, Gadd45g is expressed in stripes of primary neurons (pn) and the trigeminal placode (Vp; dorsal view). I: At larval stages, Gadd45a expression becomes weak and diffuse throughout the head and anterior trunk, and is lost from the cement gland (side view). J: At larval stages, Gadd45g expression is confined to the brain, retina, anterior spinal cord, and placode derivatives (olf, L, crg, oto, ebp; side view). K,L,M: Transverse sections at forebrain (L), hindbrain (M), rostral spinal (K) levels demonstrate neural (fb, r, hb, sc) and placodal (L, oto, crg, ebp) expression. |