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Figure 1 Developmental expression of hmgn1 in Xenopus laevis embryos. (a) At gastrula stages (NF stage 10–12), hmgn1 transcripts(hmgn1-as; upper panels) are detected throughout the embryonic ectoderm. At neurula stages (NF stage 15–18) hmgn1 appears to be enriched atthe neural plate and the neural plate border (stage 18; arrowheads). At stage 23 and 33, hmgn1 is still broadly expressed with stronger expressionin the pharyngeal arches (brackets) and the developing eyes (arrows). Stages 10–18 are dorsal views, anterior to top. Stages 23–33 are lateralviews, dorsal to top, anterior to right. Staining with a control sense probe (hmgn1-s; lower panels) is shown for comparison. (b) Transversesections of a stage 33 embryo at the forebrain (f; left panel) and hindbrain (h; right panel) levels, highlight hmgn1 expression in the skin (arrows),brain, retina of the eye (r) and to a lesser extent in the otic vesicle (o) |
