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kmt2dxenopus hindbrain 

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Experiment details for kmt2d

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis.

Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis.

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Gene Clone Species Stages Anatomy
kmt2d.L laevis NF stage 28 hindbrain

  kmt2d ( lysine methyltransferase 2D ) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 28, lateral view, anterior left, dorsal up.

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Gene Clone Species Stages Anatomy
kmt2d.L laevis NF stage 29 and 30 hindbrain

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  Figure 1: Kmt2d is expressed at early stages of Xenopus development. Kmt2d expression was analyzed by in situ hybridization. A 2-cell stage embryo. B Embryo at blastula stage 8. C Embryo at gastrula stage 10.5. D Embryo at neurula stage 14, anterior view. Arrow marks Kmt2d expression in the anterior region. E Embryo at stage 17, anterior view. F Same embryo as in E, dorsal view. G Embryo at stage 22, lateral view. H Embryo at stage 29 lateral view. I Embryo at neurula stage 14, the dashed line indicates the plane of the sagittal section shown in J. Abbreviations: a (anterior), e (eye), ea (eye anlage), ect (ectoderm), en (endoderm), m (mesoderm), s (somites), p (posterior), pn (premigratory neural crest).