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Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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nkx2-2 | xenopus |
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Experiment details for nkx2-2
The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with t...The cytoskeletal protein Zyxin inhibits Shh signaling during the CNS patterning in Xenopus laevis through interaction with the transcription factor Gli1.
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Fig. 7. Influence of Zyxin on Gli1/Shh-responsive genes in embryos with overexpressed Gli1. Embryos were injected in the same way as that in Fig. 6, except that 10 pg/embryo of Gli1 mRNA was injected instead of Shh mRNA. At stage 27, embryos were cut into successive transverse vibratome sections in the hindbrain region and four sections of each embryo were hybridized individually with probes to Pax6 (A�C), Dbx1 (E�G), Nkx2.2 (I�K) and Foxa2 (M�O). For abbreviations, see Fig. 6. |