|nkx2-2||xenopus||anterior neural fold|
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Experiment details for nkx2-2Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway.
Smurf1 regulates neural patterning and folding in Xenopus embryos by antagonizing the BMP/Smad1 pathway.
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|Fig. 5. Smurf1 knockdown disrupts neural gene expression. Anterior neural marker Otx2 (A–D), prospective eye marker Pax6 (E–H), rhombomere 3 and 5 marker Krox20 and the marker of mid-hindbrain boundary En2 (I–L) at late neurula stage 18. Pan-neural marker N-CAM at stage 18 (M–P) and stage 14 (Q, R). (S–U) Shh target gene in the neural plate, Nkx2.2, at stage 17. All are anterior views.|