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Fig. 3. Terminally differentiated cardiomyocytes retain the capacity to undergo cell division. Transverse sections of (A-C) CMO or (E-G) T5MO heart tissues at stage 37, showing cells coexpressing pH3 (red), DAPI (blue) and either (A,E) actin, (B,F) Tmy or (C,G) MHC (all shown in green). (D) Schematic of a CMO heart displaying the relative positions of each panel. A and B were imaged from an area corresponding with `A,B'; C was imaged from a region corresponding with `C'. (H) Schematic of a T5MO heart displaying the relative positions of each panel. E corresponds with `E'; F and G correspond with `F,G'. White arrows denote sarcomeric bundles. Scale bar: 10î¼ m. a, atrium; v, ventricle. |
