|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
tbxt
|
|
laevis
|
NF stage 11
|
mesoderm
,
marginal zone
,
involuting marginal zone
|
chrd
|
|
laevis
|
NF stage 11
|
mesoderm
,
marginal zone
,
dorsal marginal zone
,
upper blastopore lip
|
chrd
|
|
laevis
|
NF stage 15
|
notochord
|
sox2
|
|
laevis
|
NF stage 12
|
neural plate
,
neural plate border
|
sox2
|
|
laevis
|
NF stage 15
|
neuroectoderm
,
neural crest
,
neural plate
|
gsc
|
|
laevis
|
NF stage 11
|
mesoderm
,
marginal zone
,
dorsal marginal zone
,
upper blastopore lip
|
gsc
|
|
laevis
|
NF stage 12
|
mesoderm
,
involuted dorsal mesoderm
|
myod1
|
|
laevis
|
NF stage 15
|
mesoderm
,
presomitic mesoderm
,
paraxial mesoderm
|
|
|
Fig. 4. Arg regulated gastrulation without affecting mesodermal cell fate. A) Alteration of Arg levels did not affect expression of the mesodermal markers XBra, Chordin, Gsc and Wnt11 at gastrula stages. B) Arg modulated migration of Gsc-expressing anterior mesendoderm cells during neurulation. C) Arg regulated the shape of the expression domains of the mesodermal markers Chordin and MyoD as well as the neural marker Sox2. D) RT-PCR studies revealed that Arg did not influence mesodermal cell fate determination. |