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wnt11xenopus   

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Experiment details for wnt11

Bonacci G et al. (2012) Assay

The cytoplasmic tyrosine kinase Arg regulates gastrulation via control of actin organization.

Gene Clone Species Stages Anatomy
wnt11.S laevis NF stage 11 mesoderm , marginal zone , dorsal marginal zone , involuting marginal zone

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  Fig. 4. Arg regulated gastrulation without affecting mesodermal cell fate. A) Alteration of Arg levels did not affect expression of the mesodermal markers XBra, Chordin, Gsc and Wnt11 at gastrula stages. B) Arg modulated migration of Gsc-expressing anterior mesendoderm cells during neurulation. C) Arg regulated the shape of the expression domains of the mesodermal markers Chordin and MyoD as well as the neural marker Sox2. D) RT-PCR studies revealed that Arg did not influence mesodermal cell fate determination.