|
Fig. 1. Overall distribution of the four neural antigens
examined in tadpole stage embryos. N-CAM-PSA (highly
sialylated N-CAM) is recognized by the monoclonal
antibody 5A5 (Dodd et al. 1988), and is expressed
exclusively in the developing neural tube. The monoclonal
antibody HNK-1 (Abo and Balch, 1981) recognizes a
variety of neural and non-neural cell types, including
Rohon-Beard sensory neurons in the dorsal region of the
spinal cord (Nordlander, 1989). Antisera against the
Xenopus homeobox gene Xhox3 recognize subsets of
neurons in the midbrain, hindbrain and spinal cord (Ruiz i
Altaba et al. 1991). Antisera against the neurotransmitter
serotonin (5-HT) label a small population of cells in the
ventral region of the anterior hindbrain (van Mier et al.
1986). Arrows point to relevant regions of antigen
expression. In all cases, anterior is to the left and the
dorsal side is upwards. Scale bar=lmm. |