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Figure 2. Ngn3-GR activation affects anterior gut markers at Stage 44. (a) Exocrine pancreatic markers PDI and elastase are slightly decreased (n = 16/16 and n = 14/15, respectively). (e,f) Stomach marker cathepsin E is significantly reduced (n = 14/14). (g,h) Liver and duodenum marker hex is slightly decreased (n = 7/7). Pancreas is outlined in panels (c) and (d). |
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ctse (cathepsin E) gene expression in dissectd Xenopus laevis foregut, NF stage 44, as assayed by in situ hybridization. Lateral view: anterior left, dorsal up. |