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Fig. 4. Regulation of xCyp26c expres- sion by canonical Wnt signaling. (A) RT-PCR analysis with cDNAs synthesized using β-catenin-injected embryos. Injec- tion of β-catenin mRNA into the animal pole region of embryos decreased xCyp26c expression in a dose-dependent manner. XCyp26a expression was not clearly decreased by β-catenin injection. (B-E) Expression of xCyp26c in mid-neu- rula embryos injected into the animal pole with nothing (B,C) or β-catenin (D,E). β-catenin clearly inhibited xCyp26c ex- pression (D,E). |
