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Gene/CloneSpeciesStageAnatomy ItemExperimenter
fezf1xenopus anterior neural fold 

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Experiment details for fezf1

Rodríguez-Seguel E et al. (2009) Assay

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx.

Gene Clone Species Stages Anatomy
fezf1.S laevis NF stage 14 to NF stage 15 anterior neural fold

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  Fig. 6. Irx repress Fezf genes. All embryos are dorsal views at stage 14–15. Black and red arrowheads point at the control or injected side, respectively. (A, B) In embryos injected with Irx3-MT-GR mRNA Fezf1 is downregulated in the presence (A) but not in the absence (B) of Dex. (C, D) Injection of HD-GR-EnR mRNA caused similar Fezf1 downregulation. (E, F) In contrast, injection of HG-GR-E1A mRNA caused posterior Fezf1 expansion in the presence (E) but not in the absence of the hormone (F). (G–J) Fzf2 is also activated by HG-GR-E1A mRNA even in the presence of cycloheximide.