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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
vax1
|
|
laevis
|
NF stage 19
to
NF stage 23
|
eye primordium
|
vax2
|
|
laevis
|
NF stage 19
to
NF stage 23
|
eye primordium
|
gnpat
|
|
laevis
|
NF stage 17
|
pre-chordal neural plate
,
dorsal
,
anterior neural ridge
|
gnpat
|
|
laevis
|
NF stage 19
|
eye primordium
,
neural tube
,
anterior neural ridge
|
gnpat
|
|
laevis
|
NF stage 20
to
NF stage 22
|
forebrain
,
hindbrain
,
eye primordium
,
neural tube
|
gnpat
|
|
laevis
|
NF stage 23
|
forebrain
,
hindbrain
,
optic vesicle
,
neural tube
|
gpat3
|
|
laevis
|
NF stage 17
|
eye primordium
,
dorsal
,
anterior neural ridge
|
gpat3
|
|
laevis
|
NF stage 19
|
cement gland primordium
,
eye primordium
,
neural tube
|
gpat3
|
|
laevis
|
NF stage 20
to
NF stage 22
|
forebrain
,
hindbrain
,
eye primordium
,
neural tube
|
gpat3
|
|
laevis
|
NF stage 23
|
forebrain
,
hindbrain
,
optic vesicle
,
neural tube
|
gpat4
|
|
laevis
|
NF stage 12
to
NF stage 13
|
involuting marginal zone
|
gpat4
|
|
laevis
|
NF stage 19
|
eye primordium
,
neural tube
|
gpat4
|
|
laevis
|
NF stage 20
to
NF stage 22
|
forebrain
,
hindbrain
,
cement gland primordium
,
eye primordium
,
neural tube
|
gpat4
|
|
laevis
|
NF stage 23
|
forebrain
,
hindbrain
,
cement gland primordium
,
optic field
|
tbx3
|
|
laevis
|
NF stage 17
|
cement gland primordium
,
optic field
|
tbx3
|
|
laevis
|
NF stage 19
|
cement gland primordium
,
eye
|
tbx3
|
|
laevis
|
NF stage 20
to
NF stage 23
|
olfactory placode
,
cement gland primordium
,
eye
,
adenohypophyseal placode
|
gpam
|
|
laevis
|
NF stage 12
to
NF stage 13
|
involuting marginal zone
,
involuted dorsal mesoderm
|
gpam
|
|
laevis
|
NF stage 19
|
eye primordium
,
neural fold
|
gpam
|
|
laevis
|
NF stage 20
to
NF stage 22
|
forebrain
,
hindbrain
,
eye primordium
,
neural tube
|
gpam
|
|
laevis
|
NF stage 23
|
forebrain
,
hindbrain
,
optic vesicle
,
neural tube
|
|
|
Fig. 4. mRNA expression of GPATs and DHAPAT during neurulation and early organogenesis detected by whole-mount in situ hybridization. Expression is first detected at late gastrulation (stage 12/13) and early neurulation. All the GPATs and DHAPAT are expressed in a region around the blastopore (b) and along the anterior-posterior embryonic axis, towards the dorsal midline (dm). At stage 17, GPATs and DHAPAT are expressed in the nervous system, including the neural tube (nt), hindbrain (hb), the forebrain (fb) and the eye primordia (ep). This pattern becomes more evident at stage 19. Nervous system expression is observed in dorsal and anterior views of embryos at stage 20 and older. Vax2 and ET are two genes encoding transcription factors involved in early eye development, and were used for reference. Stage 20/22 left panel, dorsal view; Stage 17, 19, 20/22 right panel and 23, anterior view. |