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Fig. 5.
hand2 and bapx1 expression is altered in homozygous nogRMH3 mutant tadpoles. (A–D) Expression of hand2 in the head of representative WT (A,C) and homozygous nogRMH3 (B,D) tadpoles. (E–H) Expression of bapx1 in the head of representative WT (E,G) and homozygous nogRMH3 (F,H) tadpoles. (A–B,E–F) Stage 33. (C–D,G–H) Stage 39. Anterior to the left and dorsal towards the top. (M) Quantification of bapx1 expression domain shift as measured by the cement gland (CG) to otic vesicle (OV) length divided by the stained mandibular arch (MA) to eye (Ey) length. Black bars indicate wildtype embryos and open bars show mutant embryos. ** indicates p<0.05 (T-test). (A,C,E,G) Arrows show domains of expression of indicated genes in WT tadpoles. (B,D,F,H) Arrowheads show altered expression domains in homozygous nogRMH3 mutants. |