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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
src
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal pole
|
src
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
|
src
|
|
laevis
|
NF stage 16
|
neural plate
|
src
|
|
laevis
|
NF stage 28
to
NF stage 31
|
otic vesicle
,
brain
,
somite
,
pharyngeal arch
,
hyoid arch
,
[+]
|
yes1
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal hemisphere
|
yes1
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
,
non-involuting marginal zone
|
yes1
|
|
laevis
|
NF stage 16
|
neural plate
|
yes1
|
|
laevis
|
NF stage 28
to
NF stage 31
|
otic vesicle
,
brain
,
forebrain
,
hindbrain
,
spinal cord
,
[+]
|
lyn
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal pole
|
lyn
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
,
non-involuting marginal zone
|
lyn
|
|
laevis
|
NF stage 16
|
neural plate
|
myod1
|
|
laevis
|
NF stage 23
|
somite
,
myotome
,
epaxial muscle
|
myod1
|
|
laevis
|
NF stage 31
|
presomitic mesoderm
,
somite
,
tail bud
,
mouth primordium
,
myotome
,
[+]
|
csk
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal pole
|
csk
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
,
non-involuting marginal zone
|
csk
|
|
laevis
|
NF stage 16
|
neural plate
|
csk
|
|
laevis
|
NF stage 28
to
NF stage 31
|
otic vesicle
,
forebrain
,
midbrain
,
hindbrain
,
somite
,
[+]
|
hck
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal pole
|
hck
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
,
non-involuting marginal zone
|
hck
|
|
laevis
|
NF stage 16
|
neural plate
|
hck
|
|
laevis
|
NF stage 28
to
NF stage 31
|
otic vesicle
,
forebrain
,
somite
,
pharyngeal arch
,
branchial arch
,
[+]
|
fyn
|
|
laevis
|
NF stage 1
to
NF stage 8
|
animal pole
|
fyn
|
|
laevis
|
NF stage 10
to
NF stage 11
|
animal hemisphere
|
fyn
|
|
laevis
|
NF stage 16
|
neural plate
|
fyn
|
|
laevis
|
NF stage 28
to
NF stage 31
|
brain
,
forebrain
,
hindbrain
,
spinal cord
,
pharyngeal arch
,
[+]
|
|
|
Fig. 3. The spatial and temporal expression patterns of src, fyn, yes, lyn, laloo and csk mRNAs during Xenopus laevis development. (A) Animal (upper row) and lateral (lower row) view of embryonic stages 1, 2, 3 and 8 (blastula) showing enhanced signals in the animal hemisphere. (B) Animal (upper row) and vegetal (lower row) view of gastrula stages (10, 10.5, 11) showing no signal in endodermal cells. (C) Anterior and dorsal view of mid-neurula (stage 16) embryo. SFKs and csk are expressed at the neural folds from anterior to caudal end, but absent from the dorsal midline. (D,E) Lateral view of tailbud (stage 28, 31) embryos. Expression of SFKs and csk persists in the developing brain, neural tube, eye, branchial arches and otic vesicle. Bottom panels depict the expression pattern of myoD used as a positive control. First two panels show lateral and dorsal view of stage 23 embryos and the other two panels show lateral view of stage 31 embryos with the expression pattern of myoD. |
|
|
|
lyn (LYN proto-oncogene, Src family tyrosine kinase) gene expression in Xenopus laevis embryos, NF stage 28, as assayed by in situ hybridization, lateral view, anterior left, dorsal up. |