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Fig. 1. Pancreatic expression of Sox9 at stages 25-40 in whole guts and tissue sections. (A) Whole-mount in situ hybridization of Sox9 on embryonic guts at different stages. Dissected whole embryonic guts are viewed from the lateral, dorsal or ventral sides. Sox9 is detected in the dorsal (white arrows) and ventral (black arrows) pancreatic rudiments/buds from stage 25 through stage 40. Sox9 is also expressed in the lung buds (blue arrows) at stage 40. (B) Transverse sections of a stage 35/36 embryo. Sox9 is expressed in the dorsal (white arrow, upper panel) and ventral (black arrow, lower panel) pancreatic rudiments. At this stage Sox9 is also expressed in the notochord and the neural tube. ld, liver diverticulum; nt, neural tube; n, notochord; s, somite. |