|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
tacc3
|
|
laevis
|
NF stage 8
to
NF stage 9
|
embryo
|
tacc3
|
|
laevis
|
NF stage 16
|
neural plate
,
neural plate border
|
tacc3
|
|
laevis
|
NF stage 25
|
brain
,
spinal cord
,
eye
,
cranial neural crest
,
head
|
tacc3
|
|
laevis
|
NF stage 35 and 36
|
brain
,
pharyngeal arch
,
eye
,
pronephric mesenchyme
,
head
|
letm1
|
|
laevis
|
NF stage 8
to
NF stage 9
|
embryo
|
letm1
|
|
laevis
|
NF stage 16
to
NF stage 20
|
embryo
|
letm1
|
|
laevis
|
NF stage 35 and 36
|
brain
,
hyoid crest
,
intermediate mesoderm
,
eye
,
cranial neural crest
,
[+]
|
letm1
|
|
laevis
|
NF stage 39
|
brain
,
spinal cord
,
head
,
intersomitic region
|
nsd2
|
|
laevis
|
NF stage 9
|
|
nsd2
|
|
laevis
|
NF stage 16
|
neural plate
,
presumptive axial mesoderm
|
nsd2
|
|
laevis
|
NF stage 25
|
eye primordium
,
cranial neural crest
,
neural tube
|
nsd2
|
|
laevis
|
NF stage 35 and 36
|
otic vesicle
,
brain
,
eye
,
cranial neural crest
|
nsd2
|
|
laevis
|
NF stage 41
|
brain
,
hindbrain
,
spinal cord
,
cardiac mesoderm
,
rhombomere
,
[+]
|
nelfa
|
|
laevis
|
NF stage 20
|
paraxial mesoderm
,
neural tube
|
nelfa
|
|
laevis
|
NF stage 25
|
brain
,
presomitic mesoderm
,
somite
,
eye
,
cranial neural crest
|
nelfa
|
|
laevis
|
NF stage 35 and 36
|
brain
,
eye
,
cranial neural crest
|
nelfa
|
|
laevis
|
NF stage 39
|
brain
,
spinal cord
,
head
,
migratory trunk neural crest cell
|
|
|
FIGURE S1 | Expression patterns for WHS related genes across early development. In situ hybridization utilized (A–F) antisense mRNA probe to whsc1, (G–L) full-length antisense mRNA probe to whsc2, (M–R) full-length antisense mRNA probe to letm1, and (S-X) 1 kb partial-length antisense mRNA probe to tacc3. Embryos shown at blastula stage (A,G,M,S), in dorsal view at stage 16–20 (B,H,N,T), in lateral view at stage 20–25 (C,I,O,U), detail of lateral anterior region at stage 35 (D,J,P,V), and in both lateral and dorsal views from stages 39–42 (E,K,Q,W and F,L,R,X). (Y) In situ hybridization probes generated against sense strands of WHS gene mRNAs, shown at stage 25. Brown coloration (S,T) is unbleached pigment, unrelated to in situ hybridization staining. Scalebar is 250 μm.bryos were anesthetized with benzocaine. |