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Gene/CloneSpeciesStageAnatomy ItemExperimenter
tcof1xenopus anterior neural fold 

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Experiment details for tcof1

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis.

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis.

Gene Clone Species Stages Anatomy
tcof1 tegg112k11 tropicalis NF stage 14 to NF stage 15 anterior neural fold

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  Fig. 2 Expression of disease-linked ribosome biogenesis factors in X. tropicalis embryos. a Expression of all four genes was detected in the 4-cell and gastrulating embryo. Signal was strongly detected in the neural folds at stage 16 and in the migrating neural crest at stage 22. b At later stages expression of all factors was detected in the facial primordia and developing brain. Note the restricted expression at the mid–hindbrain border and forebrain. Expression was also typically detected in ventral mesoderm and hypaxial muscle precursor cells. utp4 mRNA was strongly detected at the site of the future liver. c Red lines labeled a*, b* and c* in diagrams of stage 10 and 28 embryos represent the planes of section shown in a and b

Gene Clone Species Stages Anatomy
tcof1 tegg112k11 tropicalis NF stage 18 anterior neural fold

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  Additional file 2: Comparison of digoxigenin labeled anti-sense and sense mRNA probes for each ribosomopathy gene in stage 16 embryos. Dorsal and anterior views are shown. Note the strong expression detected in the neural plate by the anti-sense mRNA probes while the control sense probed embryos remains unstained. (JPG 922 kb)