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Fig. 9. Temporal and spatial expression of TMEFF1 during early Xenopus development. (A) TMEFF1 is expressed from midgastrula stages onward. (B) At
gastrula stages (stage 11–11.5), TMEFF1 is expressed mainly in ectodermal tissues (animal), weakly in the marginal zone (DMZ and VMZ, dorsal and ventral
marginal zone, respectively), and is absent from the vegetal region. (C) Spatial expression of TMEFF1. (a) TMEFF1 is expressed in the neural plate at early
neurula stages. The embryo is viewed from the dorsal side. (b–d) As neurulation proceeds, TMEFF1 expression is enriched in the neural folds and in the
dorsal neural tube (b and d, dorsal view; c, lateral view). (e, f) At tailbud stages, TMEFF1 is detected in the diencephalon, midbrain, hindbrain, otic vesicles,
cranial nerve placodes, and the trunk dorsal neural tissue. di, diencephalon; mb, midbrain; hb, hindbrain; nt(d), neural tube (dorsal); ot, otic vesicle; pl, cranial
nerve placodes. The embryo is viewed laterally ( e) and dorsolaterally (f). |
