Search Criteria |
Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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uncx | xenopus | ectoderm [+] Bowman's gland,Eberth-Kastschenko layer,Leydig cell,Mauthner cell,Rathke's pouch,Rohon-Beard neuron,accessory olfactory bulb,adenohypophyseal placode,adenohypophysis,afferent neuron,amphibian papilla,amygdala,anterior amygdala,anterior branchial crest,anterior commissure,anterior crista,anterior entopeduncular nucleus,anterior entopeduncular region,anterior hypothalamus,anterior neural fold,anterior neural ridge,anterior neural tube,anterior neuroectoderm,anterior placodal area,anterior tectum,anterior thalamic nucleus,anterodorsal tegmental nucleus,anteroventral tegmental nucleus,astrocyte,astrocyte end-foot,auditory hair cell,auditory ossicle,auditory tube,axon,axon microtubule bundle,basal forebrain,basal ganglion,basilar papilla,bed nucleus of the stria terminalis,brain ventricle,branchial crest,buccopharyngeal membrane,cardiac neural crest,caudal tuberal region,cell body layer of the optic tectum,central amygdala,central nucleus of the thalamus,cerebellum,chordal neural crest,chordal neural plate,chordal neural plate border,chordoneural hinge,cloaca,cloacal sphincter,cranial neural crest,cranial placode,dendrite,dermis,diencephalon,dorsal column nucleus,dorsal fin margin,dorsal fin vasculature,dorsal habenular nucleus,dorsal pallidum,dorsal pallium,dorsal septum,dorsal tegmentum,dorsal telencephalon,dorsal thalamus,dorsolateral neural tube,efferent neuron,eminentia thalami,endolymphatic duct,enteric neuron,epidermal cell,epidermis,epidermis inner layer,epidermis outer layer,external plexiform layer of the olfactory bulb,fin crest,fin margin,fin vasculature,footplate of the stapes,forebrain,forebrain-midbrain boundary,fourth ventricle,frontal nerve,glomerular layer of the olfactory bulb,goblet cell,granule cell,granule cell layer of the cerebellum,granule cell layer of the olfactory bulb,growth cone,habenula,hatching gland cell,hatching gland primordium,hindbrain,hyoid crest,hypophysis,hypothalamus,infundibulum,inner ear,inner fin,interneuron,ionocyte,isthmic nucleus,keratinocyte,lagena,lateral amygdala,lateral crista,lateral forebrain bundle,lateral ganglionic eminence,lateral hypothalamic nucleus,lateral pallium,lateral preplacodal ectoderm,lateral septum,laterodorsal tegmental nucleus,lens epithelium,lens fiber cell mass,lens placode,lens transitional zone,locus coeruleus,magnocellular preoptic nucleus,mammilary region,mandibular crest,mandibular nerve,maxillary nerve,medial amygdala,medial ganglionic eminence,medial pallium,medial septum,medulla oblongata,melanotrope,mesencephalic artery,mesencephalic vein,metencephalic artery,metencephalic vein,midbrain,midbrain tegmentum,midbrain-hindbrain boundary,middle ear,migrating macrophage,migratory neural crest cell,migratory trunk neural crest cell,mitral cell,mitral cell layer of the olfactory bulb,mucociliary epithelium,nasociliary nerve,neural crest,neural fold,neural groove,neural plate,neural plate border,neural stem cell,neurenteric canal,neurocoel,neuroectoderm inner layer,neuroectoderm outer layer,neurohypophysis,neuromast mantle cell,neuromast support cell,neuron projection,neuropil of the optic tectum,notoplate,nucleus accumbens,nucleus of the diagonal band,nucleus of the solitary tract,nucleus reticularis inferior,nucleus reticularis medialis,nucleus reticularis superior,oculomotor motornucleus,olfactory bulb,olfactory sensory neuron,oligodendrocyte,optic chiasm,optic field,optic stalk,optic tectum,optic tract,oral cavity,oral epithelium,osseous labyrinth,otic capsule,outer fin,oval window,pallidum,pallium,pars distalis,pars externa of the stapes,pars intermedia,pars interna of the stapes,pars media of the stapes,pars nervosa,peripheral nerve,pia mater,pial cell,pigment cell,pineal gland,posterior branchial crest,posterior commissure,posterior crista,posterior hypothalamus,posterior neural fold,posterior neural tube,posterior placodal area,posterior tectum,posterior wall of neurenteric canal,posterodorsal tegmental nucleus,posteroventral tegmental nucleus,postmigratory neural crest cell,pre-chordal neural plate,pre-chordal neural plate border,premigratory neural crest cell,preoptic area,preplacodal ectoderm,pretectum,prethalamus,prethalamus basal plate,prootic bone,prosomere,prosomere 4,prosomere 5,prosomere 6,radial glial cell,raphe nucleus,rectal diverticulum,retromammillary area,rhombic lip,rhombomere,roof of mouth,rostral tuberal region,saccular macula,sacral neural crest,semicircular canal,sensorial layer of neurectoderm,skin gland,small secretory cell,solitary tract,stapes,stratum compactum,stratum spongiosum,stria terminalis,striatum,subcommissural organ,subpallium,subthalamic nucleus,sulcus limitans of neural tube,superficial layer of neurectoderm,suprachiasmatic nucleus,supraoptoparaventricular region,telencephalon,telencephalon septum,thalamus,third ventricle,torus semicircularis,trochlear motornucleus,trunk neural crest,tuberal region,tympanic annulus,tympanic disk,vagal neural crest,ventral fin vasculature,ventral habenular nucleus,ventral hypothalamic nucleus,ventral pallidum,ventral pallium,ventral septum,ventral tegmentum,ventricular layer of the optic tectum,ventricular zone,ventrolateral neural tube,ventrolateral thalamic nucleus,ventromedial thalamic nucleus,vestibular apparatus,vestibule,zona limitans intrathalamica,Jacobson's organ,Rathke's pouch,adrenal medulla,afferent neuron,anterior branchial crest,anterior neural ridge,anterior neuroectoderm,astrocyte,astrocyte end-foot,auditory apparatus,brain,branchial crest,buccopharyngeal membrane,caudal lateral line,cement gland,cement gland primordium,choana,chordal neural crest,circumpharyngeal ridge,claw,claw primordium,cloacal sphincter,cornea,cranial placode,dorsal lateral line,dorsal tail fin,dorsolateral placode region,ectodermal cell,efferent neuron,enteric nervous system,enteric neuron,epibranchial placode,epidermis,fin,fin margin,gasserian ganglion,glial cell,hatching gland,hatching gland primordium,hypobranchial placode,hypophyseal primordium,hypophysis,lateral preplacodal ectoderm,lens,lens placode,melanoblast,melanophore,middle lateral line,migrating neuroblast,migratory neural crest cell,mouth,mouth primordium,neural crest,neural fold,neural groove,neural plate border,neural stem cell,neural tube,neuroectoderm,neurogenic placode,neuron,non-ciliated epithelial cell,non-neural ectoderm,non-neurogenic ectodermal placode,oculomotor motornucleus,olfactory epithelium,olfactory nerve,olfactory organ,olfactory pit,olfactory placode,oligodendrocyte,otic capsule,otic placode,otic vesicle,peripheral ganglion,pigment cell,posterior branchial crest,preplacodal ectoderm,proctodeum,radial glial cell,regenerating lens,sacral neural crest,secretory epithelial cell,sensorial layer,skin,small secretory cell,stomodeal-hypophyseal primordium,tail bud,tooth,trigeminal ganglion,trigeminal nerve,trigeminal placode,trunk neural crest,trunk placode,unicellular gland,vagal neural crest,vagus nerve,ventral lateral line,vestibulocochlear ganglion,zona limitans intrathalamica |
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Experiment details for uncx
Yan B et al. (2015) AssayMicroarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development.
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Figure 4. Whole-mount in situ hybridization assays at early developmental stages illustrating the common expression patterns of 14 up-regulated genes: Nrp1, Arrb2, BG022063, LOC100037047, BQ399495, Hrpt1, Rbm42-6, LOC414689, Uncx4.1, Xxylt1, Nfya, Tbc1d31, Cdca7l, Papd4-a. For all genes, expression is enhanced in the animal cells (an) of cleavage and blastula embryos (side views). At gastrula stages, expression is throughout the ectoderm, occasionally enhanced in the animal cells (e.g., Arrb2) or the dorsal cells (e.g., Nrp1) (side views). At early neural plate stages, all genes are expressed in the epidermis (epi), often more intensely on the dorsal (d) side, including neural plate (np) and border zone (bz) (all except Nrp1 are side views with anterior [a] to the left; Nrp1 is an anterior view with dorsal to the top). At late neural plate and neural tube stages, expression is strongest in the neural crest (nc), pre-placodal region (ppr), neural tube (nt) and occasionally cement gland (cem) (all are anterior views). For Nrp1, embryos were sectioned in the horizontal plane to demonstrate that the ppr stripe in the whole embryo is due to expression in the deep (d) layer of the ectoderm, not the superficial (s) layer of the ectoderm or the pharyngeal endoderm (phe); ph, lumen of pharynx. | |||||||||||
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Figure 5. Whole-mount in situ hybridization assays at tail bud to larval stages illustrating more divergent expression patterns of 14 up-regulated genes: Nrp1, Arrb2, BG022063, LOC100037047, BQ399495, Hrpt1, Rbm42-6, LOC414689, Uncx4.1, Xxylt1, Nfya, Tbc1d31, Cdca7l, Papd4-a. Side views at tail bud (left column) and larval (middle column) stages, with anterior to the left and dorsal to the top, and transverse sections at larval stages (right side) with dorsal to the top. ba, branchial arches; cem, cement gland; ep, epibranchial placodes; epi, epidermis; fb, forebrain; h, heart; hb, hindbrain; IX/Xg, glossopharyngeal/vagal ganglion; l, lens; mb, midbrain; ne, nephric mesoderm; olf, olfactory placode; oto, otocyst; p, pineal; r, retina; spcd, spinal cord; so, somites; Vg, trigeminal ganglion; VIIg, facial ganglion. |