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Fig. 1. Developmental expression of C1qA. (A) Bissected gastrula. Dorsal is to the right. Expression is restricted to the marginal zone mesoderm indicated by the arrow;(b) blastpore, (m) mesoderm. (B) Stage 28 embryo. Anterior is to the left and dorsalto the top. There is strong expression in the cephalic structures, especially in the branchial arches (ba) and in the otic vesicle (ov). Expression in the intersomitic veins is visible (isv). Pronephric expression has begun (pr). The small arrows indicate expression in the pronephric duct. (C) Stage 35 embryo shows detailed expression in pronephros (pr) and duct. At this stage, expression in the lateral muscle presursors (small arrows) is visible ventral to the duct. (D) Transverse section through an age- matched embryo to (C). The section is at the level of the pronephros. Dorsal is to the top. Somitic expression is most pronounced in the cells adjacent to the neural tube (nt) as indicated by the small arrows, and in the pronephros (pr). There is no staining in the notochord (n). (E) Ventral view of a stage 35 embryo reveals staining consistent with ventral blood island expression (arrow). |
