Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
cbfa2t2xenopus eye 

Too many results?Too few results?

Experiment details for cbfa2t2

Logan MA et al. (2005) Assay

Identification of shared transcriptional targets for the proneural bHLH factors Xath5 and XNeuroD.

Gene Clone Species Stages Anatomy
cbfa2t2.L laevis NF stage 41 to NF stage 42 eye

Display additional annotations [+]
  Fig. 5. Proneural bHLH target genes are expressed in late progenitors or post-mitotic neurons of the X. laevis retina. (A) Schematic of stage 41/42 X. laevis retinal cross-section. The central retina contains post-mitotic cells stratified into 3 major layers: retinal ganglion cell (RGC) layer, inner nuclear layer (INL) and outer nuclear layer (ONL). The ciliary marginal zone (CMZ) contains retinal stem cells within the most peripheral region (per) and early differentiating progenitors within the central region (cntl). The entire neural retina is surrounded by retinal pigment epithelium (RPE). (B) In situ hybridizations were performed on paraffin sections of stage 41/42 X. laevis embryos. (B) Xath5 expression is restricted to the central CMZ (bracket) and excluded from the most peripheral CMZ. (C) SBT1, Xgadd45γ and XETOR, respectively, are also restricted to progenitors and early differentiating neurons within the central CMZ (bracket). (F) elrC is expressed in differentiating neurons in the most central CMZ region (arrow in panel F) and persists in post-mitotic cells of the RGC layer and a subset of cells within the INL. (G) Xebf3 expression is also present in differentiating neurons of the central CMZ (arrow in panel G) and maintained in mature RGCs.