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Fig. 4. Expression pattern for the wdr68 gene during Xenopus early development. (A, B) Dorsal view of embryo. (C–F) Side view. (G, H) Transverse sections. (A) wdr68 expression is ubiquitous during early stages of development. (B, C) Since the late neurula stage, there is an enrichment in its expression in the head region (black arrowhead in B), in the migratory streams of the cranial neural crest (black arrowheads in C) and in the developing somites (white arrow). (D) At stage 25, wdr68 transcripts are evident in the otic vesicle. In the somitic region (black arrow), they acquire a segmental pattern. (E, F) Since the tailbud stage, wdr68 is strongly marked in the branchial arches (brackets). (G) Front section at the level of the branchial arches (blue broken line in F). Notice that the ectodermal cell population corresponding to the neural crest expresses wdr68. (H) Transverse section at the trunk level (red broken line in F). wdr68 expression is evident on the floor of the neural tube and in somitic mesoderm. References: BA, branchial arches; CNC, cranial neural crest; Ect, ectoderm; OpV, optic vesicle; OtV, otic vesicle; n, notochord; NC, neural crest; NT, neural tube. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) |
