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Figure 1 Expression patterns of FGFFs in Xenopus hindlimb regeneration pression of xFGFR-1 in a 15-day blastema after amputation of a stage 53 hindlimb . Note the high expression (depicted as blue color) in the wound epithelium (we), the blastema (b), perichondrium (p), and cartilage (c). B, Expression of xFGFR-1 in a 15-day regenerate after amputation of a stage 61 hindlimb, There is some ex- pression in the mesenchyme (m), but the wound epithelium is negative. C. Expresssion of xFGFR-4b in a 15-day blastema
after amputation of a stage 53 hindlimb Similar to xFGFR-1, note the expression in the wound epithelium and the under- neath mesenchymal cells of the blastema. D, Expression of xFGFR-4b in a 15-day regenerate after amputation of a
stage 61 hindlimb.Note the expression in the blastema and in the basal layer of the wound epithelium. E and F, Hybridization with a sense probe (xFGFR-1) to show the background in a 15-day regenerate after amputation of a stage 53 and stage 61 hindlimb, respectively.
Reproduced with permission of the publisher, John Wiley & Sons. |
