Search Criteria |
Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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glis2 | xenopus | midbrain [+] |
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Experiment details for glis2
Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation.Identification of NKL, a novel Gli-Kruppel zinc-finger protein that promotes neuronal differentiation.
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Fig. 2. Expression pattern of NKL in mouse, chick and Xenopus embryos. (A-C) In mouse, mNKL is expressed in the intermediate zone (arrows) of E10.5 hindbrain (A) and spinal cord (B), as well as in the DRG (arrowhead in B). At E12.5 mNKL is expressed in a narrow band of cells in the ventricular zone (vz) (C). In chick stage 25 embryos (D) cNKL is expressed in the intermediate zone (arrow) of the spinal cord as it is in the E10.5 mouse. (E) In Xenopus stage 13.5 embryos staining is apparent in the neural plate in lateral (L) and medial (M) stripes of primary neurons. (F) An anterior view of a stage 19 embryo indicates NKL hybridization in the trigeminal ganglion (arrow). (G) A dorsal view of columns of NKL-positive cells in the neuraxis (arrow). Note also the onset of NKL staining in the branchial arches (arrowhead). In tailbud stage (32) embryos NKL staining is seen in the neuraxis, the head, the eye and the branchial arches (H). (I,J) Transverse vibratome sections taken immediately posterior to the hindbrain through the neural tube of stage 24 embryos stained for NKL (I) and N-tubulin (J). |