|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
dll1
|
|
laevis
|
NF stage 26
|
otic vesicle
,
forebrain
,
hindbrain
,
spinal cord
,
eye
,
[+]
|
sox3
|
|
laevis
|
NF stage 26
|
olfactory placode
,
otic vesicle
,
lens
,
forebrain
,
midbrain
,
[+]
|
tubb2b
|
|
laevis
|
NF stage 26
|
hindbrain
,
spinal cord
,
profundus ganglion
,
trigeminal ganglion
,
facial nerve
|
neurod1
|
|
laevis
|
NF stage 26
|
olfactory placode
,
otic vesicle
,
eye
,
epibranchial placode
,
lateral line placode
|
cdknx
|
|
laevis
|
NF stage 26
|
olfactory placode
,
otic vesicle
,
hindbrain
,
spinal cord
,
eye
,
[+]
|
|
|
Fig. 5. Effects of overexpression of GR–Eya1 or GR–Eya1+GR–Six1 on various neurogenesis markers at tail bud stages (stage 26). Injected (A1–N1) and control (A2–N2) sides of tail bud stage embryos after unilateral injection of GR–Eya1 (A–H) or GR–Eya1+GR–Six1 (I–N) and DEX activation at stage 16–18. In all cases, where myc-GFP was co-injected as lineage tracer (A–F, I–M), embryos are shown superimposed with green fluorescent channel. Black asterisks indicate reductions, while black or white arrows mark increased or ectopic marker gene expression in the placodal or non-neural ectoderm. Yellow asterisks identify expression in pharyngeal pouches. For NeuroD (C, D) and p27Xic1 (G, H) after GR–Eya1 injection two different phenotypes are depicted. Abbreviations as in Fig. 2 and Fig. 4. |