|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
tcof1
|
|
tropicalis
|
NF stage 3 (4-cell)
|
animal blastomere
,
animal
,
blastomere
,
animal pole
|
tcof1
|
|
tropicalis
|
NF stage 10
|
dorsal
|
tcof1
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
anterior neural fold
,
posterior
|
tcof1
|
|
tropicalis
|
NF stage 22
|
branchial crest
,
optic vesicle
,
cranial neural crest
|
tcof1
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
otic vesicle
,
brain
,
midbrain-hindbrain boundary
,
pharyngeal arch
,
mandibular arch
,
[+]
|
utp4
|
|
tropicalis
|
NF stage 3 (4-cell)
|
|
utp4
|
|
tropicalis
|
NF stage 10
|
|
utp4
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
anterior neural fold
|
utp4
|
|
tropicalis
|
NF stage 22
|
branchial crest
,
cranial neural crest
,
posterior
|
utp4
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
midbrain-hindbrain boundary
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
branchial arch
,
[+]
|
utp4
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
liver
,
head
|
sbds
|
|
tropicalis
|
NF stage 3 (4-cell)
|
|
sbds
|
|
tropicalis
|
NF stage 10
|
|
sbds
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
cranial neural crest
,
posterior
|
sbds
|
|
tropicalis
|
NF stage 22
|
mandibular crest
,
hyoid crest
,
branchial crest
,
cranial neural crest
,
posterior
|
sbds
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
otic vesicle
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
branchial arch
,
[+]
|
sbds
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
head
|
rbm28
|
|
tropicalis
|
NF stage 3 (4-cell)
|
|
rbm28
|
|
tropicalis
|
NF stage 10
|
animal hemisphere
|
rbm28
|
|
tropicalis
|
NF stage 14
to
NF stage 15
|
cranial neural crest
|
rbm28
|
|
tropicalis
|
NF stage 22
|
mandibular crest
,
hyoid crest
,
branchial crest
,
cranial neural crest
|
rbm28
|
|
tropicalis
|
NF stage 28
to
NF stage 29 and 30
|
otic vesicle
,
midbrain-hindbrain boundary
,
ventral blood island
,
pharyngeal arch
,
mandibular arch
,
[+]
|
rbm28
|
|
tropicalis
|
NF stage 35 and 36
to
NF stage 40
|
otic vesicle
,
brain
,
midbrain-hindbrain boundary
,
eye
,
pharynx
|
|
|
Fig. 2
Expression of disease-linked ribosome biogenesis factors in X. tropicalis embryos. a Expression of all four genes was detected in the 4-cell and gastrulating embryo. Signal was strongly detected in the neural folds at stage 16 and in the migrating neural crest at stage 22. b At later stages expression of all factors was detected in the facial primordia and developing brain. Note the restricted expression at the mid–hindbrain border and forebrain. Expression was also typically detected in ventral mesoderm and hypaxial muscle precursor cells. utp4 mRNA was strongly detected at the site of the future liver. c Red lines labeled a*, b* and c* in diagrams of stage 10 and 28 embryos represent the planes of section shown in a and b |
|
|
|
tcof1 (Treacher Collins-Franceschetti syndrome 1) gene expression in Xenopus tropicalis embryo, assayed via in situ hybridization, NF stage 28, lateral view, anterior left, dorsal up. |