XB-ART-18896Nature December 7, 1995; 378 (6557): 578-83.
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Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
The highly conserved protein gamma-tubulin is required for microtubule nucleation in vivo. When viewed in the electron microscope, a highly purified gamma-tubulin complex from Xenopus consisting of at least seven different proteins is seen to have an open ring structure. This complex acts as an active microtubule-nucleating unit which can cap the minus ends of microtubules in vitro.
PubMed ID: 8524390
Article link: Nature
Species referenced: Xenopus
Genes referenced: tubg1