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Neuron December 1, 1995; 15 (6): 1383-92.

Two classes of olfactory receptors in Xenopus laevis.

Freitag J , Krieger J , Strotmann J , Breer H .

Xenopus laevis possess a gene repertoire encoding two distinct classes of olfactory receptors: one class related to receptors of fish and one class similar to receptors of mammals. Sequence comparison indicates that the fish-like receptors represent closely related members of only two subfamilies, whereas mammalian-like receptors are more distantly related, most of them representing a different subfamily. The fish-like receptor genes are exclusively expressed in the lateral diverticulum of the frog''s nose, specialized for detecting water-soluble odorants, whereas mammalian-like receptors are expressed in sensory neurons of the main diverticulum, responsible for the reception of volatile odors.

PubMed ID: 8845161
Article link: Neuron