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XB-ART-19454
Gene 1995 Jul 28;1602:207-11. doi: 10.1016/0378-1119(95)00176-7.
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The cDNA encoding Xenopus laevis heat-shock factor 1 (XHSF1): nucleotide and deduced amino-acid sequences, and properties of the encoded protein.

Stump DG , Landsberger N , Wolffe AP .


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We have isolated a cDNA encoding Xenopus laevis (Xl) heat-shock factor 1 (XHSF1). XHSF1, translated from the mRNA synthesized in vitro, will bind specifically to the Xl hsp70 promoter (hsp70). Microinjection of XHSF1 mRNA into Xl oocytes leads to synthesis of XHSF1 which accumulates in the nucleus and selectively activates Xl phsp70p activity at 18 degrees C.

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Species referenced: Xenopus laevis
Genes referenced: hsf1 hsp70 hspa1l