XB-ART-22603
FEBS Lett
1993 May 03;3221:6-9.
Show Gene links
Show Anatomy links
Chaperonins dependent increase of Cu,Zn superoxide dismutase production in Escherichia coli.
???displayArticle.abstract???
Over-expression of the chaperonins GroEL and GroES significantly suppressed the temperature-dependent pattern of expression of Cu,Zn superoxide dismutases in Escherichia coli and increased the yield of active enzyme. The results obtained indicate that chaperonins prevent degradation of metal-deficient enzyme molecules. GroEL was shown to form a complex with unfolded Cu,Zn superoxide dismutase in vitro, confirming that GroEL can interact with beta-stranded proteins.
???displayArticle.pubmedLink??? 8097729
???displayArticle.link??? FEBS Lett
Species referenced: Xenopus laevis
Genes referenced: hspd1