Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-26512
Nature 1989 Sep 07;3416237:33-8. doi: 10.1038/341033a0.
Show Gene links Show Anatomy links

Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.

Ruiz i Altaba A , Melton DA .


???displayArticle.abstract???
The expression of the Xenopus homoeobox gene xhox3 is an early response to mesoderm induction by peptide growth factors and the level of xhox3 expression marks the antero-posterior character of the induced mesoderm. Different peptide growth factors specify different antero-posterior mesodermal cell fates as seen by the level of xhox3 expression and the capacity to induce specific secondary neural/epidermal structures. These factors and homoeobox genes thus form part of the mechanism necessary for establishing antero-posterior polarity in the frog embryo.

???displayArticle.pubmedLink??? 2570357
???displayArticle.link??? Nature


Species referenced: Xenopus laevis
Genes referenced: evx1